Chemical informatics for libraries

presentation references

 

Jeffery Loo

NLM Associate Fellow ’03-’05

www.jeffloo.com

 

 

Excellent resources

 

Chemoinformatics: a textbook. 

Gasteiger J, Engel T, eds.  Weinheim, Germany:Wiley-VCH;2003.

 

Handbook of chemoinformatics: from data to knowledge. (4 volumes)

Johann Gasteiger, ed. Weinheim, Germany:Wiley-VCH;2003.

 

 

Definitions

 

Chemoinformatics: What is it and How does it Impact Drug Discovery. 

Brown FK. Annual Reports in Medicinal Chemistry. 1998;33:375-384.

 

Introduction.

Gasteiger J. In: Gasteiger J, Engel T, eds.  Chemoinformatics: a Textbook.  Weinheim, Germany:Wiley-VCH;2003: Chapter 1.

 

Understanding chemoinformatics: a unifying approach.

Bajorath J. Drug Discovery Today. 2004 Jan 1;9(1):13-4.

 

What is chemical informatics?

Wiggins G. Indiana University.

www.indiana.edu/~cheminfo/informatics/cinform_whatis.html

last updated 16 July 2004; last accessed 4 July 2005.

 

Editorial opinion: chemoinformatics - a ten year update.

Brown F. Curr Opin Drug Discov Devel. 2005 May;8(3):298-302.

 

 

Chemistry – growth in chemical data

 

Chemoinformatics: a Textbook. 

Gasteiger J. In: Gasteiger J, Engel T, eds. Weinheim, Germany:Wiley-VCH;2003.

 

Handbook of chemoinformatics: from data to knowledge. (4 volumes)

Johann Gasteiger, ed. Weinheim, Germany:Wiley-VCH;2003.

 

Combinatorial chemistry and new drugs.

Plunkett MJ, Ellman JA. Scientific American. 1997 Apr:68-73.

 

 

Chemical biology – growth in data

 

A community of chemists and biologists.

Editorial. Nature Chemical Biology. 2005 Jun;1(1):3.

 

Chemistry & Biology: Partners in Decoding the Genome

NHGRI & NIGMS, National Institutes of Health

Conference, March 15-16, 2004, with lecture webcasts

http://www.genome.gov/11008534

 

 

Small molecule chemistry

 

From knowing to controlling: a path from genomics to drugs using small molecule probes.

Strausberg RL, Schreiber SL. Science. 2003 Apr 11;300(5617):294-5.

[full text]

 

Diversity-oriented synthesis: exploring the intersections between chemistry and biology.

Tan DS. Nature Chemical Biology. 2005 Jul;1(2):74-84.

 

 

High throughput screening – growth in  data

 

High-throughput screening for drug discovery.

Broach JR, Thorner J. Nature. 1996 Nov 7;384(6604 Suppl):14-6.

 

 

Small molecule informatics infrastructure

 

ChemBank Initiative for Chemical Genetics

http://chembank.broad.harvard.edu/

 

PubChem

http://pubchem.ncbi.nlm.nih.gov/

 

NIH Chemical Genomics Center

http://www.genome.gov/12512295

 

Molecular Libraries Screening Centers Network

http://grants1.nih.gov/grants/guide/rfa-files/RFA-RM-04-017.html

 

NIH Molecular Libraries Initiative.

Austin CP, Brady LS, Insel TR, Collins FS. Science. 2004 Nov 12;306(5699):1138-9.

[full text]

 

 

Information acquisition and sharing and the library professional

 

Chemistry in bioinformatics.

Murray-Rust P, Mitchell JB, Rzepa HS. BMC Bioinformatics. 2005 Jun 7;6(1):141.

[free full text]

 

Information management and the library professional

 

SPECTRa: Submission, Preservation and Exposure of Chemistry Teaching and Research Data

http://www.jisc.ac.uk/index.cfm?name=project_spectra

 

WorldWideMolecularMatrix

http://www.dspace.cam.ac.uk/handle/1810/724

 

 

Information use and the library professional

 

Information for Chemists -- Soft/ware

Chemistry software listing

http://www.chem.ac.ru/Chemistry/Soft/

 

Tom’s Free Chemistry Software

http://users.ugent.be/~tkuppens/chem/

 

The informationist: a new health profession?

Davidoff F, Florance V. Ann Intern Med. 2000 Jun 20;132(12):996-8.

[free full text]

 

 

MSc Chemical informatics programs

 

Chemistry plans a structural overhaul.

Russo E. Nature. 2002 Sep 12;419(6903):4-7.

[full text]

 

Indiana University

http://www.informatics.indiana.edu/academics/chem.asp

 

The University of Manchester

http://www.manchester.ac.uk/degreeprogrammes/postgraduate/taught/1107.htm

 

The University of Sheffield

http://www.shef.ac.uk/is/courses/pg_mscci.html

 

University of Massachusetts Lowell

(computer science program with chemoinformatics option)

http://genome.uml.edu/programs_grad.htm

 

 

Library service models

 

A library-based bioinformatics services program. 

Yarfitz S, Ketchell DS. Bull Med Libr Assoc. 2000 Jan;88(1):36-48. [free full text]

 

A model for training the new bioinformationist.

Lyon J, Giuse NB, Williams A, Koonce T, Walden R. J Med Libr Assoc. 2004 Apr;92(2):188-95. [free full text]

 

Research Informatics Consult Service

Eskind Biomedical Library, Vanderbilt University

http://www.mc.vanderbilt.edu/biolib/services/rics/

 

BioResearcher Toolkit

University of Washington Health Sciences Libraries

http://healthlinks.washington.edu/index.jsp?id=210BCCB7-511A-4C6B-8B40-DFC47AABEA7F